Lynn K Barrett Selected Research

Cryptosporidiosis

1/2021	One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases.
1/2021	Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of Cryptosporidiosis.
7/2020	Conducting clinical trials in sub-Saharan Africa: challenges and lessons learned from the Malawi Cryptosporidium study.
1/2019	P-Glycoprotein-Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium.
1/2019	Development of 5-Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
1/2018	7 H-Pyrrolo[2,3- d]pyrimidin-4-amine-Based Inhibitors of Calcium-Dependent Protein Kinase 1 Have Distinct Inhibitory and Oral Pharmacokinetic Characteristics Compared with 1 H-Pyrazolo[3,4- d]pyrimidin-4-amine-Based Inhibitors.
10/2017	Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.
1/2017	Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection.
1/2017	Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.
1/2017	5-Aminopyrazole-4-Carboxamide-Based Compounds Prevent the Growth of Cryptosporidium parvum.

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Lynn K Barrett Research Topics

Disease

12	Cryptosporidiosis 01/2021 - 12/2016
12	Infections 01/2021 - 08/2003
4	Cardiotoxicity 01/2019 - 01/2016
3	Toxoplasmosis 01/2021 - 01/2016
3	Diarrhea 07/2020 - 01/2017
3	Syphilis 07/2004 - 08/2003
2	COVID-19 01/2021 - 01/2021
2	Communicable Diseases (Infectious Diseases) 01/2021 - 01/2020
2	Tuberculosis (Tuberculoses) 08/2016 - 03/2015
2	Brucellosis (Malta Fever) 01/2016 - 01/2016
1	Amebiasis (Amoebiasis) 11/2021
1	Stillbirth 09/2020
1	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2020
1	Coinfection 01/2020
1	Parasitic Diseases (Parasitic Disease) 01/2020
1	Body Weight (Weight, Body) 01/2019
1	Bacillary Dysentery (Shigellosis) 01/2019
1	Fever (Fevers) 01/2018
1	Malaria 01/2017
1	Glucosephosphate Dehydrogenase Deficiency 01/2017
1	Congenital Toxoplasmosis 01/2017
1	Eye Infections 01/2017
1	Persistent Infection 12/2016
1	Encephalomyelitis (Myeloencephalitis) 12/2016
1	Bites and Stings (Sting) 01/2016
1	Babesiosis (Piroplasmosis) 01/2016
1	Zoonoses 01/2016
1	Lyme Disease (Disease, Lyme) 08/2003
1	Relapsing Fever 08/2003
1	Leptospirosis 08/2003

Drug/Important Bio-Agent (IBA)

16	Pharmaceutical PreparationsIBA 11/2021 - 03/2015
12	Phosphotransferases (Kinase)IBA 01/2021 - 12/2016
8	calcium-dependent protein kinaseIBA 01/2021 - 01/2016
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2003
3	AntigensIBA 01/2021 - 08/2003
3	AntibodiesIBA 01/2019 - 08/2003
2	pyrrolopyrimidineIBA 01/2021 - 01/2019
2	BKI-1553IBA 01/2018 - 12/2016
2	Ether (Diethyl Ether)IBA 01/2017 - 01/2016
2	CalciumIBA 12/2016 - 12/2016
2	Methionine-tRNA LigaseIBA 01/2016 - 01/2016
1	Recombinant ProteinsIBA 01/2021
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 01/2021
1	NucleoproteinsIBA 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	VaccinesIBA 01/2021
1	imidazoleIBA 01/2021
1	pyrimidineIBA 01/2021
1	Fertility AgentsIBA 09/2020
1	Clofazimine (Lamprene)FDA Link 07/2020
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2020
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2020
1	Ampicillin (Omnipen)FDA LinkGeneric 01/2019
1	Ciprofloxacin (Cipro)FDA LinkGeneric 01/2019
1	BKI 1369IBA 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 01/2019
1	toltrazurilIBA 01/2019
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2019
1	AminesIBA 01/2018
1	Immunoglobulin G (IgG)IBA 01/2018
1	NaphthoquinonesIBA 01/2017
1	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2017
1	buparvaquoneIBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	EnzymesIBA 01/2017
1	Potassium Channels (Potassium Channel)IBA 01/2017
1	Indicators and Reagents (Reagents)IBA 01/2017
1	prolyl T RNA synthetaseIBA 01/2017
1	Protein Kinases (Protein Kinase)IBA 12/2016
1	Thomsen-Friedenreich antibodiesIBA 08/2003

Therapy/Procedure

12	Therapeutics 01/2021 - 01/2016
1	Drug Therapy (Chemotherapy) 01/2017
1	Aftercare (After-Treatment) 12/2016
1	Blood Transfusion (Blood Transfusions) 01/2016